Quercetin is being widely studied for a host of benefits that boost health and performance of healthy individuals as well as those battling various conditions.
Athletic Performance Properties
Quercetin has been shown to enhance performance in two double-blind, placebo-controlled crossover studies on cyclists. The first one was done using a Quercetin-containing beverage at Pepperdine University by Dr. Holden MacRae. Elite cyclists over a 3 week period on a simulated 30km mountainous time trial showed a 3.1% improvement in time when they consumed the Quercetin product over the placebo. Dr. MacRae said of the results, “Exercise performance changes of 1-4% are significant and usually mean the difference between winning and losing. Changes of this magnitude are typically achieved in athletes only by blood doping or living at high altitude.” A second study examined the effects of 14 days of supplementation with Quercetin at 1,000 mg per day on 26 untrained adult males. Results showed a statistically significant increase in quercetin blood plasma levels, and a 2.9% improvement in treadmill time trial performance and a non-significant directional increase of 4.1% in muscle mitochondria DNA compared to the control.
Upper Respiratory Tract Infection Properties
A randomized, double-blind, placebo controlled clinical study at Appalachian State showed that the antioxidant quercetin significantly reduced incidence of upper respiratory tract illness during the two-week period following intensified exercise. Forty test subjects were subjected to extreme physical stress during a five-week period. Half were given 1,000 mg of quercetin daily and half were given a placebo. While markers of immunity did not differ significantly between the quercetin and placebo groups, in the quercetin group, the incidence of upper respiratory tract infection was significantly reduced (1 out of 20), while in the placebo group, 9 out of 20 athletes experienced infection.
Quercetin has been found to be a powerful anti-inflammatory. Inflammation in the body leads to many health ailments and diseases. Arthritis is caused by inflammation between the joints. A report in the 2008 issue of the "Journal of Pre-Clinical and Clinical Research" (JPCCR) states that Quercetin acts quickly within the body and can ease arthritis pain within two to three days. (The amount of quercetin in this study was 750 mg daily, provided through supplements.) A study in the July 2008 medical journal "Metabolism" verifies the JPCCR report that Quercetin is an anti-inflammatory, stating that it is found to be effective in reducing signs of inflammation within the blood.
The American Academy of Family Physicians describes histamines as substances that irritate the cells in the body. This is why they cause sneezing, itching, and other allergy type reactions. An antihistamine prevents these symptoms by not allowing histamines to attach to and irritate the cells. The University of Maryland Medical Center reports that, in test tube studies, Quercetin is shown to prevent the release of histamines.
Quercetin has been found to both treat and prevent cancers in certain studies. Notwithstanding this the Company does not make any cancer treatment claims for its products and will not make any such claims without following the recognized FDA procedures. The June 11, 2009 issue of the "Journal of Experimental and Clinical Cancer Research" shows that Quercetin is found to be protective against the formation of liver cancer cells, mainly due to its role as an antioxidant. Quercetin is also found to treat cancer by causing apoptosis, or "cell death," as reported in the May 18, 2009 edition of the medical journal, "Phytotherapy Research." While these studies are promising, most have been performed on mice and rats but not on humans. The American Cancer Society (ACS) reports a human study in which the combination of Quercetin and curcumin supplements decrease the size and quantity of rectal tumors. The stand of the ACS is that they would like to see more clinical trials on the effects of Quercetin on cancer in humans before recommending supplements. However, they do promote adding Quercetin to the diet by increasing your daily intake of fresh fruit and vegetables.
Anti-Heart Disease Properties
Quercetin is known to have protective benefits when it comes to heart disease. The April 4, 2008 edition of the "Journal of Biological Chemistry" reports a study that shows the powerful action of Quercetin against cardiovascular disease. In this study, they find that Quercetin goes directly to the areas of the arteries that are injured or inflamed, while passing over healthy areas. The University of Maryland Medical Center also reports that Quercetin may protect against the build up of plaque in the arteries and the LDL (bad) cholesterol damage.
Quercegen is not making these claims regarding its Q-Force product, but is highlighting some of the positive research done on Quercetin as an ingredient.